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Motilium Fastmelts are used to treat nausea and vomiting in adults and adolescents over 12 years old and over 35kg in bodyweight

How to Use

The usual dose is one tablet up to three times a day, if possible, before meals. Place the tablet on the tongue, where it melts and is swallowed with saliva.

Do not take Motilium if you:

  • Are allergic to domperidone, the active ingredient, or any of the other ingredients gelatin, mannitol, aspartame, mint flavouring, poloxamer 80.
  • Have stomach bleeding, regularly have severe abdominal cramps or persistant black stools
  • Have a tumour of the pituitary gland
  • Have PKU or phenylketonuria (Motilium contains aspartame and should be avoided)
  • Have moderate or severe liver disease
  • Have had an ECG that showed a heart problem with a prolonged QT interval
  • Have heart failure, or the heart is insufficiently pumping blood around the body
  • Have low potassium or magnesium levels or high potassium levels in your blood

Do not take If you are taking any of the following medicines:

  1. Antifungals specifically ketoconazole, fluconazole or voriconazole
  2. Antibiotics specifically erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine
  3. Heart medication specifically amiodarone, dronedarone, quinidine, sotalol, diltiazem, verapamil
  4. Antipsychotics such as haloperidol,pimozide,sertindole
  5. Antidepressants such as citalopram,escitalopram
  6. Gastro intestinal disorder treatment such as cisapride, dolasetron,prucalopride
  7. Allergy medication mizolastine, mequitazine
  8. Antimalarials espcially halofantrine
  9. HIV/AIDS treatment called protease inhibitors
  10. Cancer treatment toremifine,vandetanib, vincamine



Motilium Fastmelts are an orodispersible tablet containing 10mg Domperidone.